Impaired cognitive function in healthy offspring of bipolar patients

Materials and methods Fifty persons (17 male, 33 female), aged 18-52 (30 ± 7) years made the total adult offspring population of patients with bipolar mood disorder. Among them, two had a history of depressive episodes, and another eight scored positively on Mood Disorder Questionnaire [4]. The head-to-head ageand gender-matched healthy subjects were used as a comparison group. The computer version of WCST designed by Heaton et al. (1993) adapted with instructions in Polish was used in all subjects. The following domains of WCST were measured: the percentage of perseverative errors (WCST-P), the percentage of non-perseverative errors (WCST-NP), the number of correctly completed categories (WCST-CC), the percentage of conceptual level responses (WCST-% conc), and the set to the first category (WCST-1st cat).